Publications

Rubio-Navarro A, Gómez-Banoy N, Stoll L, Dündar F, Mawla AM, Ma L, Cortada E, Zumbo P, Li A, Reiterer M et al..  2023.  A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes.. Nat Cell Biol. 25(4):565-578.

Li H, Korcari A, Ciufo D, Mendias CL, Rodeo SA, Buckley MR, Loiselle AE, Pitt GS, Cao C.  2023.  Increased Ca 2+ signaling through Ca V 1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties.. bioRxiv.

Li H, Korcari A, Ciufo D, Mendias CL, Rodeo SA, Buckley MR, Loiselle AE, Pitt GS, Cao C.  2023.  Increased Ca2+ signaling through CaV 1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties.. FASEB J. 37(7):e23007.

Wang G, Li J, Bojmar L, Chen H, Li Z, Tobias GC, Hu M, Homan EA, Lucotti S, Zhao F et al..  2023.  Tumour extracellular vesicles and particles induce liver metabolic dysfunction.. Nature. 618(7964):374-382.

Kushner JS, Liu G, Eisert RJ, Bradshaw GA, Pitt GS, J Hinson T, Kalocsay M, Marx SO.  2022.  Detecting Cardiovascular Protein-Protein Interactions by Proximity Proteomics.. Circ Res. 130(2):273-287.

Liu H, Wang H-G, Pitt GS, Liu ZJ.  2022.  Direct Observation of Compartment-Specific Localization and Dynamics of Voltage-Gated Sodium Channels.. J Neurosci. 42(28):5482-98.

Ghazizadeh Z, Zhu J, Fattahi F, Tang A, Sun X, Amin S, Tsai S-Y, Khalaj M, Zhou T, Samuel RM et al..  2022.  A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells.. iScience. 25(4):104153.

Matsui M, Bouchareb R, Storto M, Hussain Y, Gregg A, Marx SO, Pitt GS.  2022.  Increased Ca2+ influx through CaV1.2 drives aortic valve calcification.. JCI Insight. 7(5)

Papa A, Zakharov SI, Katchman AN, Kushner JS, Chen B-X, Yang L, Liu G, Jimenez ASanchez, Eisert RJ, Bradshaw GA et al..  2022.  Rad regulation of CaV1.2 channels controls cardiac fight-or-flight response.. Nat Cardiovasc Res. 1(11):1022-1038.

Han Y, Zhu J, Yang L, Nilsson-Payant BE, Hurtado R, Lacko LA, Sun X, Gade AR, Higgins CA, Sisso WJ et al..  2022.  SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells.. Circ Res. 130(7):963-977.

Papa A, Kushner J, Hennessey JA, Katchman AN, Zakharov SI, Chen B-X, Yang L, Lu R, Leong S, Diaz J et al..  2021.  Adrenergic CaV1.2 Activation via Rad Phosphorylation Converges at α1C I-II Loop.. Circ Res. 128(1):76-88.

Wang H-G, Bavley CC, Li A, Jones RM, Hackett JE, Bayleyen Y, Lee FS, Rajadhyaksha AM, Pitt GS.  2021.  Scn2a severe hypomorphic mutation decreases excitatory synaptic input and causes autism-associated behaviors.. JCI Insight.

Joglekar A, Prjibelski A, Mahfouz A, Collier P, Lin S, Schlusche AKatharina, Marrocco J, Williams SR, Haase B, Hayes A et al..  2021.  A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain.. Nat Commun. 12(1):463.

Pitt GS, Matsui M, Cao C.  2021.  Voltage-Gated Calcium Channels in Nonexcitable Tissues.. Annu Rev Physiol. 83:183-203.

Wang Z, Vermij SH, Sottas V, Shestak A, Ross-Kaschitza D, Zaklyazminskaya EV, Hudmon A, Pitt GS, Rougier J-S, Abriel H.  2020.  Calmodulin binds to the N-terminal domain of the cardiac sodium channel Nav1.5.. Channels (Austin). 14(1):268-286.

Balestrini S, Mikati MA, Álvarez-García-Rovés R, Carboni M, Hunanyan AS, Kherallah B, McLean M, Prange L, De Grandis E, Gagliardi A et al..  2020.  Cardiac phenotype in ATP1A3-related syndromes: A multicenter cohort study.. Neurology. 95(21):e2866-e2879.

Abrams J, Roybal D, Chakouri N, Katchman AN, Weinberg R, Yang L, Chen B-X, Zakharov SI, Hennessey JA, Avula UMahesh R et al..  2020.  Fibroblast growth factor homologous factors tune arrhythmogenic late NaV1.5 current in calmodulin binding-deficient channels.. JCI Insight. 5(19)

Gade AR, Marx SO, Pitt GS.  2020.  An interaction between the III-IV linker and CTD in NaV1.5 confers regulation of inactivation by CaM and FHF.. J Gen Physiol. 152(2)

Liu G, Papa A, Katchman AN, Zakharov SI, Roybal D, Hennessey JA, Kushner J, Yang L, Chen B-X, Kushnir A et al..  2020.  Mechanism of adrenergic Ca1.2 stimulation revealed by proximity proteomics.. Nature. 577(7792):695-700.

Cao C, Oswald AB, Fabella BA, Ren Y, Rodriguiz R, Trainor G, Greenblatt MB, Hilton MJ, Pitt GS.  2019.  The Ca1.2 L-type calcium channel regulates bone homeostasis in the middle and inner ear.. Bone. 125:160-168.

Pitt GS, Lee S-Y.  2019.  Ca/CaM interaction with voltage-gated Na channels.. Proc Natl Acad Sci U S A.

Yang L, Katchman A, Kushner J, Kushnir A, Zakharov SI, Chen B-X, Shuja Z, Subramanyam P, Liu G, Papa A et al..  2019.  Cardiac CaV1.2 channels require β subunits for β-adrenergic-mediated modulation but not trafficking.. J Clin Invest. 129(2):647-658.

Sinden DS, Holman CD, Bare CJ, Sun X, Gade AR, Cohen DE, Pitt GS.  2019.  Knockout of the X-linked in the hypothalamic paraventricular nucleus impairs sympathetic output to brown fat and causes obesity.. FASEB J. 33(10):11579-11594.

Abraham DM, Lee TE, Watson LJ, Mao L, Chandok G, Wang H-G, Frangakis S, Pitt GS, Shah SH, Wolf MJ et al..  2018.  The two-pore domain potassium channel TREK-1 mediates cardiac fibrosis and diastolic dysfunction.. J Clin Invest. 128(11):4843-4855.

Pitt GS.  2018.  An update on the journey towards precision medicine in cardiology.. Eur Heart J. 39(40):3627-3628.