Publications

Naderi J, Johnson AKelsey, Thakkar H, Chandravanshi B, Ksiazek A, Anand A, Vincent V, Tran A, Kalimireddy A, Singh P et al..  2025.  Ceramide-induced FGF13 impairs systemic metabolic health.. Cell Metab. 37(5):1206-1222.e8.

Much C, Rajkumar SM, Chen L, Cohen JM, Gade AR, Pitt GS, Long Y.  2025.  Distinct specificity and functions of PRC2 subcomplexes in human stem cells and cardiac differentiation.. Mol Cell. 85(16):3057-3073.e10.

Das LTanmoy, Malvezzi M, Gade A, Matsui M, McKay M, Wei EQ, Zelich MJ, Mazdisnian K, Kushner J, Chen B-X et al..  2025.  FGF13 Regulates VGSC-Independent Cardiomyocyte Impulse Propagation via Cx43 Trafficking.. Circ Res.

Lin S, Gade AR, Wang H-G, Niemeyer JE, Galante A, DiStefano I, Towers P, Nunez J, Matsui M, Schwartz TH et al..  2025.  Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism.. Elife. 13

Gade AR, Malvezzi M, Das LTanmoy, Matsui M, Ma C-IJ, Mazdisnian K, Marx SO, Maxfield FR, Pitt GS.  2025.  The NaV1.5 auxiliary subunit FGF13 modulates channels by regulating membrane cholesterol independent of channel binding.. J Clin Invest. 135(20)

Lin S, Schwartz TH, Pitt GS.  2025.  Sudden unexpected death in epilepsy: respiratory vs. cardiac contributions.. Cardiovasc Res. 120(18):2385-2394.

Katchman AN, Zakharov SI, Bohnen MS, Jimenez ASanchez, Kushner JS, Yang L, Chen B-X, Nasari A, Liu G, Rabbani DE et al..  2024.  Augmented Cardiac Inotropy by Phosphodiesterase Inhibition Requires Phosphorylation of Rad and Increased Calcium Current.. Circulation. 149(20):1617-1620.

Papa A, Morfin PJDel Rive, Chen B-X, Yang L, Katchman AN, Zakharov SI, Liu G, Bohnen MS, Zheng V, Katz M et al..  2024.  A membrane-associated phosphoswitch in Rad controls adrenergic regulation of cardiac calcium channels.. J Clin Invest. 134(5)

Matsui M, Lynch LE, DiStefano I, Galante A, Gade AR, Wang H-G, Gómez-Banoy N, Towers P, Sinden DS, Wei EQ et al..  2024.  Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome.. Nat Commun. 15(1):8980.

Pitt GS, Long Y.  2024.  Mutations of Splicing Regulator RBM20 in Atrial Fibrillation.. JACC Basic Transl Sci. 9(2):181-184.

Timothy KW, Bauer R, Larkin KA, Walsh EP, Abrams DJ, Corcia CGonzalez, Valsamakis A, Pitt GS, Dick IE, Golden A.  2024.  A Natural History Study of Timothy Syndrome.. Orphanet J Rare Dis. 19(1):433.

Rubio-Navarro A, Gómez-Banoy N, Stoll L, Dündar F, Mawla AM, Ma L, Cortada E, Zumbo P, Li A, Reiterer M et al..  2023.  A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes.. Nat Cell Biol. 25(4):565-578.

Li H, Korcari A, Ciufo D, Mendias CL, Rodeo SA, Buckley MR, Loiselle AE, Pitt GS, Cao C.  2023.  Increased Ca 2+ signaling through Ca V 1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties.. bioRxiv.

Li H, Korcari A, Ciufo D, Mendias CL, Rodeo SA, Buckley MR, Loiselle AE, Pitt GS, Cao C.  2023.  Increased Ca2+ signaling through CaV 1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties.. FASEB J. 37(7):e23007.

Wang G, Li J, Bojmar L, Chen H, Li Z, Tobias GC, Hu M, Homan EA, Lucotti S, Zhao F et al..  2023.  Tumour extracellular vesicles and particles induce liver metabolic dysfunction.. Nature. 618(7964):374-382.

Kushner JS, Liu G, Eisert RJ, Bradshaw GA, Pitt GS, J Hinson T, Kalocsay M, Marx SO.  2022.  Detecting Cardiovascular Protein-Protein Interactions by Proximity Proteomics.. Circ Res. 130(2):273-287.

Liu H, Wang H-G, Pitt GS, Liu ZJ.  2022.  Direct Observation of Compartment-Specific Localization and Dynamics of Voltage-Gated Sodium Channels.. J Neurosci. 42(28):5482-98.

Ghazizadeh Z, Zhu J, Fattahi F, Tang A, Sun X, Amin S, Tsai S-Y, Khalaj M, Zhou T, Samuel RM et al..  2022.  A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells.. iScience. 25(4):104153.

Matsui M, Bouchareb R, Storto M, Hussain Y, Gregg A, Marx SO, Pitt GS.  2022.  Increased Ca2+ influx through CaV1.2 drives aortic valve calcification.. JCI Insight. 7(5)

Papa A, Zakharov SI, Katchman AN, Kushner JS, Chen B-X, Yang L, Liu G, Jimenez ASanchez, Eisert RJ, Bradshaw GA et al..  2022.  Rad regulation of CaV1.2 channels controls cardiac fight-or-flight response.. Nat Cardiovasc Res. 1(11):1022-1038.

Han Y, Zhu J, Yang L, Nilsson-Payant BE, Hurtado R, Lacko LA, Sun X, Gade AR, Higgins CA, Sisso WJ et al..  2022.  SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells.. Circ Res. 130(7):963-977.

Papa A, Kushner J, Hennessey JA, Katchman AN, Zakharov SI, Chen B-X, Yang L, Lu R, Leong S, Diaz J et al..  2021.  Adrenergic CaV1.2 Activation via Rad Phosphorylation Converges at α1C I-II Loop.. Circ Res. 128(1):76-88.

Wang H-G, Bavley CC, Li A, Jones RM, Hackett JE, Bayleyen Y, Lee FS, Rajadhyaksha AM, Pitt GS.  2021.  Scn2a severe hypomorphic mutation decreases excitatory synaptic input and causes autism-associated behaviors.. JCI Insight.

Joglekar A, Prjibelski A, Mahfouz A, Collier P, Lin S, Schlusche AKatharina, Marrocco J, Williams SR, Haase B, Hayes A et al..  2021.  A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain.. Nat Commun. 12(1):463.

Pitt GS, Matsui M, Cao C.  2021.  Voltage-Gated Calcium Channels in Nonexcitable Tissues.. Annu Rev Physiol. 83:183-203.