Pitt Lab

Publications

Found 41 results
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Sinden DS, Holman CD, Bare CJ, Sun X, Gade AR, Cohen DE, Pitt GS.  2019.  Knockout of the X-linked in the hypothalamic paraventricular nucleus impairs sympathetic output to brown fat and causes obesity.. FASEB J. 33(10):11579-11594.
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Sun AY, Pitt GS.  2016.  Long QT Syndrome and Seizures.. JACC Clin Electrophysiol. 2(3):277-278.
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Liu G, Papa A, Katchman AN, Zakharov SI, Roybal D, Hennessey JA, Kushner J, Yang L, Chen B-X, Kushnir A et al..  2020.  Mechanism of adrenergic Ca1.2 stimulation revealed by proximity proteomics.. Nature. 577(7792):695-700.
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Wang H-G, Zhu W, Kanter RJ, Silva JR, Honeywell C, Gow RM, Pitt GS.  2016.  A novel NaV1.5 voltage sensor mutation associated with severe atrial and ventricular arrhythmias.. J Mol Cell Cardiol. 92:52-62.
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Pablo JLorenzo, Wang C, Presby MM, Pitt GS.  2016.  Polarized localization of voltage-gated Na+ channels is regulated by concerted FGF13 and FGF14 action.. Proc Natl Acad Sci U S A. 113(19):E2665-74.
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Papa A, Zakharov SI, Katchman AN, Kushner JS, Chen B-X, Yang L, Liu G, Jimenez ASanchez, Eisert RJ, Bradshaw GA et al..  2022.  Rad regulation of CaV1.2 channels controls cardiac fight-or-flight response.. Nat Cardiovasc Res. 1(11):1022-1038.
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Han Y, Zhu J, Yang L, Nilsson-Payant BE, Hurtado R, Lacko LA, Sun X, Gade AR, Higgins CA, Sisso WJ et al..  2022.  SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells.. Circ Res. 130(7):963-977.
Wang H-G, Bavley CC, Li A, Jones RM, Hackett JE, Bayleyen Y, Lee FS, Rajadhyaksha AM, Pitt GS.  2021.  Scn2a severe hypomorphic mutation decreases excitatory synaptic input and causes autism-associated behaviors.. JCI Insight.
Joglekar A, Prjibelski A, Mahfouz A, Collier P, Lin S, Schlusche AKatharina, Marrocco J, Williams SR, Haase B, Hayes A et al..  2021.  A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain.. Nat Commun. 12(1):463.
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Black JB, Adler AF, Wang H-G, D'Ippolito AM, Hutchinson HA, Reddy TE, Pitt GS, Leong KW, Gersbach CA.  2016.  Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells.. Cell Stem Cell. 19(3):406-14.
Wang G, Li J, Bojmar L, Chen H, Li Z, Tobias GC, Hu M, Homan EA, Lucotti S, Zhao F et al..  2023.  Tumour extracellular vesicles and particles induce liver metabolic dysfunction.. Nature. 618(7964):374-382.
Abraham DM, Lee TE, Watson LJ, Mao L, Chandok G, Wang H-G, Frangakis S, Pitt GS, Shah SH, Wolf MJ et al..  2018.  The two-pore domain potassium channel TREK-1 mediates cardiac fibrosis and diastolic dysfunction.. J Clin Invest. 128(11):4843-4855.
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Pitt GS.  2018.  An update on the journey towards precision medicine in cardiology.. Eur Heart J. 39(40):3627-3628.
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Pitt GS.  2016.  A view from the side-line.. Eur Heart J. 37(47):3488-3489.
Pitt GS, Matsui M, Cao C.  2021.  Voltage-Gated Calcium Channels in Nonexcitable Tissues.. Annu Rev Physiol. 83:183-203.
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Choi J-I, Wang C, Thomas MJ, Pitt GS.  2016.  α1-Syntrophin Variant Identified in Drug-Induced Long QT Syndrome Increases Late Sodium Current.. PLoS One. 11(3):e0152355.