Publications

Matsui M, Lynch LE, DiStefano I, Galante A, Gade AR, Wang H-G, Gómez-Banoy N, Towers P, Sinden DS, Wei EQ et al..  2024.  Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome.. Nat Commun. 15(1):8980.

Much C, Rajkumar SM, Chen L, Cohen JM, Gade AR, Pitt GS, Long Y.  2025.  Distinct specificity and functions of PRC2 subcomplexes in human stem cells and cardiac differentiation.. Mol Cell. 85(16):3057-3073.e10.

Naderi J, Johnson AKelsey, Thakkar H, Chandravanshi B, Ksiazek A, Anand A, Vincent V, Tran A, Kalimireddy A, Singh P et al..  2025.  Ceramide-induced FGF13 impairs systemic metabolic health.. Cell Metab. 37(5):1206-1222.e8.

Pablo JLorenzo, Wang C, Presby MM, Pitt GS.  2016.  Polarized localization of voltage-gated Na+ channels is regulated by concerted FGF13 and FGF14 action.. Proc Natl Acad Sci U S A. 113(19):E2665-74.

Pablo JLorenzo, Pitt GS.  2017.  FGF14 is a regulator of KCNQ2/3 channels.. Proc Natl Acad Sci U S A. 114(1):154-159.

Pablo JLorenzo, Pitt GS.  2017.  Divide, multitask, and conquer: Coordination in channel regulation.. Channels (Austin). :1-3.

Papa A, Morfin PJDel Rive, Chen B-X, Yang L, Katchman AN, Zakharov SI, Liu G, Bohnen MS, Zheng V, Katz M et al..  2024.  A membrane-associated phosphoswitch in Rad controls adrenergic regulation of cardiac calcium channels.. J Clin Invest. 134(5)

Papa A, Kushner J, Hennessey JA, Katchman AN, Zakharov SI, Chen B-X, Yang L, Lu R, Leong S, Diaz J et al..  2021.  Adrenergic CaV1.2 Activation via Rad Phosphorylation Converges at α1C I-II Loop.. Circ Res. 128(1):76-88.

Papa A, Zakharov SI, Katchman AN, Kushner JS, Chen B-X, Yang L, Liu G, Jimenez ASanchez, Eisert RJ, Bradshaw GA et al..  2022.  Rad regulation of CaV1.2 channels controls cardiac fight-or-flight response.. Nat Cardiovasc Res. 1(11):1022-1038.

Pitt GS, Long Y.  2024.  Mutations of Splicing Regulator RBM20 in Atrial Fibrillation.. JACC Basic Transl Sci. 9(2):181-184.

Pitt GS, Lee S-Y.  2019.  Ca/CaM interaction with voltage-gated Na channels.. Proc Natl Acad Sci U S A.

Pitt GS.  2018.  An update on the journey towards precision medicine in cardiology.. Eur Heart J. 39(40):3627-3628.

Pitt GS, Matsui M, Cao C.  2021.  Voltage-Gated Calcium Channels in Nonexcitable Tissues.. Annu Rev Physiol. 83:183-203.

Pitt GS.  2016.  A view from the side-line.. Eur Heart J. 37(47):3488-3489.

Pitt GS, Lee S-Y.  2016.  Current view on regulation of voltage-gated sodium channels by calcium and auxiliary proteins.. Protein Sci. 25(9):1573-84.

Rubio-Navarro A, Gómez-Banoy N, Stoll L, Dündar F, Mawla AM, Ma L, Cortada E, Zumbo P, Li A, Reiterer M et al..  2023.  A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes.. Nat Cell Biol. 25(4):565-578.

Sinden DS, Holman CD, Bare CJ, Sun X, Gade AR, Cohen DE, Pitt GS.  2019.  Knockout of the X-linked in the hypothalamic paraventricular nucleus impairs sympathetic output to brown fat and causes obesity.. FASEB J. 33(10):11579-11594.

Sun AY, Pitt GS.  2016.  Long QT Syndrome and Seizures.. JACC Clin Electrophysiol. 2(3):277-278.

Timothy KW, Bauer R, Larkin KA, Walsh EP, Abrams DJ, Corcia CGonzalez, Valsamakis A, Pitt GS, Dick IE, Golden A.  2024.  A Natural History Study of Timothy Syndrome.. Orphanet J Rare Dis. 19(1):433.

Wang G, Li J, Bojmar L, Chen H, Li Z, Tobias GC, Hu M, Homan EA, Lucotti S, Zhao F et al..  2023.  Tumour extracellular vesicles and particles induce liver metabolic dysfunction.. Nature. 618(7964):374-382.

Wang H-G, Zhu W, Kanter RJ, Silva JR, Honeywell C, Gow RM, Pitt GS.  2016.  A novel NaV1.5 voltage sensor mutation associated with severe atrial and ventricular arrhythmias.. J Mol Cell Cardiol. 92:52-62.

Wang H-G, Bavley CC, Li A, Jones RM, Hackett JE, Bayleyen Y, Lee FS, Rajadhyaksha AM, Pitt GS.  2021.  Scn2a severe hypomorphic mutation decreases excitatory synaptic input and causes autism-associated behaviors.. JCI Insight.

Wang X, Tang H, Wei EQ, Wang Z, Yang J, Yang R, Wang S, Zhang Y, Pitt GS, Zhang H et al..  2017.  Conditional knockout of Fgf13 in murine hearts increases arrhythmia susceptibility and reveals novel ion channel modulatory roles.. J Mol Cell Cardiol. 104:63-74.

Wang Z, Vermij SH, Sottas V, Shestak A, Ross-Kaschitza D, Zaklyazminskaya EV, Hudmon A, Pitt GS, Rougier J-S, Abriel H.  2020.  Calmodulin binds to the N-terminal domain of the cardiac sodium channel Nav1.5.. Channels (Austin). 14(1):268-286.

Wei EQ, Sinden DS, Mao L, Zhang H, Wang C, Pitt GS.  2017.  Inducible Fgf13 ablation enhances caveolae-mediated cardioprotection during cardiac pressure overload.. Proc Natl Acad Sci U S A. 114(20):E4010-E4019.